Coronavirus Vaccine Trial Adverse Reactions

There are at least 17 vaccine trials going on right now to develop a vaccine for SARS-CoV-2, the virus that is said to cause covid-19 infections. At this time, it’s a bit hard to analyze each trial because they are mostly still ongoing. It was hard to find links to the research data. However, here are a few articles that have been put out regarding some of the reactions in early human trials.

This article below attempts to make it a point that if the public wants to shut down people speaking about what they deem to be “vaccine misinformation”, then the media needs to start talking about the adverse reactions instead of pretending they don’t exist. It actually brings out some good information such as the fact that vaccines are not tested against a placebo. Instead they are usually tested against the meningococcal vaccine, which has a slew of side effects on it’s own. Then they compare the two groups to see if there is a significant difference in adverse reactions. Only one, the Oxford vaccine, is testing against a true saline placebo according to the article.

“By the time they’d had two doses, every single one was showing signs of headaches, chills, or fatigue, and for at least 80 percent, this could have been enough to interfere with their normal activities. A participant who had a severe reaction to a particularly high dose has  about how bad it was: If reactions even half as bad as this were to be common for some of these vaccines, they will be hard sells once they reach the community—and there could be a lot of people who are reluctant to get the second injection.

“Clinical trials for other Covid-19 vaccines have placebo groups, where participants receive saline injections. Only one of the Oxford vaccine trials is taking this approach, however; the others instead compare the experimental treatment to an injected meningococcal vaccine.”

Participates also had to be able to take acetaminophin in order to join the trial. They were given a dose of acetaminophen every 6 hours for 24 hours, and they still had fevers and adverse reactions.
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The Lancet has an article about a vaccine that China is developing. They talk about possibly recommending this for children, but noone under the age of 18 is in the trials.

“Fifth, in this study, no participants had SARS-CoV-2 exposure after the vaccination, so we were unable to assess the efficacy of the candidate vaccine or any immunological risk associated with antibody induced by vaccination when exposed to the virus. However, the risk of COVID-19 and antibody-enhanced disease on exposure to the virus will be monitored long term”
It’s worth noting that the younger the participants, the higher the rate of developing a fever was. At least 90% of the younger participants developed fevers.
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Here is another article where one of the participants in Moderna’s vaccine trial speaks about his severe reaction. He went to the hospital with 103 degree fever and sickness and was given fever reducers and sent home. He ended up fainting at home but decided not to go back to the hospital. He said it is the sickest he has ever been in his life, but he still believes in the vaccine and doesn’t want people to use his reaction against the vaccine.

“He and his girlfriend arrived home at 7 a.m., and he slept until noon. His temperature was 101.5. He got up to go to the bathroom, and became so nauseous he threw up. On his way back from the bathroom, he fainted. His girlfriend caught him and kept his head from hitting the floor. 

She then called one of the doctors working in the study, and asked what they should do. The doctor told them he could go back to urgent care, or call 911, and reminded them that all his medical costs would be covered by the study.

But he got to a couch and was given sports drinks. He spent the afternoon there, with a wet towel on his head, fighting the fever. By 9:45 p.m., it was back down to 99.1. It tapered off. He says he felt better within a few days, and has had no side effects since. 

Haydon said the experience left him as sick as he’d ever felt. But standard flu-like symptoms that resolve within a day are not necessarily considered a reason not to use a vaccine that prevents a more serious illness.”

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That’s another article about the “minor” side effection in the majority of trial participants.

If a vaccine causes the same symptoms and sickness as covid-19, what good is it? The majority of people who contract the coronavirus will recover and only have mild symptoms. There are a lot of numbers being thrown out for the death rate. From 0.26-3.0% being listed. It’s probably safe to say that at around 99% of people who are positive for covid-19 survive. If you take a vaccine that makes you sicker than you would have been catching the actual virus, many people won’t be interested in that. Additionally, no long term research studies have been done yet. None of the studies seem to be looking specifically for autoimmunity.

Stay tuned for upcoming information on the use of messenger RNA.

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